
Electric patches are adhesive patches that are used in the medical field for various purposes. They are used to deliver medication to targeted areas, providing localized treatment for pain, inflammation, and other conditions. These patches are also used to stop bacterial infections without using any drugs. They can also be used to treat mental health issues such as PTSD by sending a low-level current to cranial nerves while the person sleeps. Additionally, electromagnetic cellularized patches are used to promote neuronal differentiation and spinal cord injury repair.
| Characteristics | Values |
|---|---|
| Purpose | To deliver medication, treat bacterial infections, treat PTSD, or for muscle pain relief |
| Mechanism | Sends a low-level electrical current to the skin or cranial nerves |
| Benefits | Drug-free treatment, targeted relief, simple technology |
| Use Cases | Skin infections, wound healing, pain relief, inflammation, PTSD, epilepsy, depression |
| Limitations | Only effective in an acidic environment for bacterial treatment |
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What You'll Learn

Treating PTSD
An electrical patch placed on the forehead, known as external Trigeminal Nerve Stimulation (eTNS or TNS), has shown promising results in treating chronic PTSD. The treatment involves using a 9-volt battery to generate a weak electric current that stimulates the cranial nerves in the forehead while the patient sleeps. This stimulation sends signals to parts of the brain that regulate mood, behaviour, and cognition, including the amygdala, medial prefrontal cortex, and the autonomic nervous system, which exhibit abnormal activity in people with PTSD.
The UCLA-led study included 12 participants with chronic PTSD and severe depression who continued their conventional treatments, such as psychotherapy and medication, during the trial. The participants wore the patch for eight hours every night for eight weeks. Before and after the treatment, they filled out questionnaires about their symptoms and how they affected their daily lives. The results showed a significant improvement, with a reduction of over 30% in PTSD symptoms and over 50% in depression severity. Moreover, one-quarter of the participants experienced PTSD symptom remission, and they reported feeling more capable of engaging in daily activities.
The next phase of the research will involve military veterans, who are at a higher risk of developing PTSD. This study will be conducted similarly to a drug trial, with half of the participants receiving the real TNS treatment and the other half receiving a fake patch. At the end of the study, those who used the placebo patch will have the option to undergo treatment with an actual TNS system.
The eTNS treatment for PTSD is a breakthrough, especially for those who have not found relief from current treatments. It offers a drug-free approach to managing PTSD symptoms and improving the overall quality of life for those affected.
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Spinal cord injury repair
An electromagnetic cellularized patch is a wireless technology that can generate electrical stimulation under a changing magnetic field to promote neuronal differentiation and spinal cord injury repair. The patch is made of graphite nanosheets, a material that conducts electricity and is biocompatible, i.e., non-toxic to cells.
Spinal cord injury (SCI) is a severely disabling neurological condition with symptoms of impaired mobility, pain, and autonomic dysfunction. The dead or damaged spinal neurons at the injury site cause the paralysis of denervated musculature and the disruption of long spinal tracts, resulting in the loss of sensation and motor control.
In preliminary studies, the patch has been shown to significantly improve healing in mouse models and even act as a protective layer for the spinal cord. The electric pulses delivered by the patch increase the proportion of stem cells that differentiate into mature neurons. The patch also does not trigger inflammation, indicating that it may not need to be removed, thus minimizing the total number of surgeries.
The frequency and strength of the electrical signal can be tuned by varying the rotation speed of the magnetic field. The patch-mediated wireless electrical stimulation promotes the differentiation of neural stem cells and the repair of injured spinal cord tissue.
Other biomaterial-based regenerative therapeutic strategies for spinal cord injury include the use of alginate hydrogels, agarose scaffolds, conductive polymers, and electrospinning techniques to fill cavities, restore anatomical continuity, improve motor function, and promote axon regeneration and tissue regeneration.
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Combating bacterial infections
Bacterial infections are caused by harmful bacteria entering and multiplying in the body. They can affect many parts of the body, including the skin, lungs, brain, and blood. Common bacterial infections include urinary tract infections (UTIs), food poisoning, sexually transmitted infections (STIs), and skin, sinus, and ear infections. These infections are often treated with antibiotics. However, in some cases, bacteria may be resistant to antibiotics, leading to persistent infections.
To combat bacterial infections, here are some measures that can be taken:
Preventative Measures
Good hygiene practices, such as regular handwashing with soap and clean water or using hand sanitizers, can help reduce the risk of bacterial infections. This is especially important after using the toilet, before handling food, and after coughing, sneezing, or blowing your nose. Additionally, practicing food safety by properly handling and cooking food can prevent foodborne bacterial infections.
Vaccines
Vaccines are an effective tool to prevent and reduce the spread of bacterial infections. They work by training the body's immune system to recognize and fight against specific bacteria or infections. Vaccines are routinely used in both human and veterinary medicine to protect against various diseases, such as bacterial pneumonia.
Probiotics
Probiotics, often referred to as 'good bacteria,' are beneficial microorganisms that can improve gut health and overall wellbeing. By maintaining a healthy balance of gut bacteria, probiotics can help prevent bacterial infections in the digestive system. Probiotics are commonly used in animal feed and are increasingly recognized as a valuable addition to human diets as well.
Phage Therapy
Phage therapy, or bacteriophage therapy, is an experimental approach to treating bacterial infections. Bacteriophages are viruses that specifically target and kill bacteria. They have shown promising results in animal studies, but their effectiveness in humans is still being researched. Phage therapy may offer an alternative treatment option for antibiotic-resistant bacteria in the future.
Electric Current Therapy
Recently, researchers have developed a skin patch that delivers weak electric currents to control microbes and treat bacterial infections. This approach, known as Bioelectronic Localized Antimicrobial Stimulation Therapy (BLAST), has been successful in stopping 99% of biofilm formation, a cluster of bacteria that blocks drugs, under ideal acidic conditions. This drug-free treatment method holds exciting potential for wound healing and combating antibiotic-resistant bacteria.
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Muscle and joint pain relief
Transcutaneous Electrical Nerve Stimulation (TENS) is a method for relieving muscle and joint pain. It involves using sticky electrode patches attached to a small, battery-operated device. The patches are placed on the skin, delivering an electric current to the nerves, which overrides pain signals. This can also trigger the release of natural painkillers (endorphins) in the brain. TENS is generally considered safe, but it is important to consult a doctor first if you have a pacemaker, an implanted device, are pregnant, have epilepsy, or heart problems.
There are also prescription pain-relief patches that can be used for muscle and joint pain. These include lidocaine patches, which are local anaesthetics that block nerves from sending pain signals. Diclofenac epolamine patches are another option, containing a non-steroidal anti-inflammatory medication. Fentanyl patches are also available but are strong opioids, so caution must be exercised, and they are generally only prescribed to those who have previously tolerated opioid medications.
For arthritis pain specifically, there are electrical nerve stimulation treatments. These include Percutaneous Electrical Stimulation (PES), which delivers a current to the site of pain via electrodes on the skin, and Neuromuscular Electrical Stimulation (NMES), which applies electrical impulses to nerves to contract muscles and strengthen joints. Spinal cord stimulation is another option, which involves surgically implanting a wire under the skin to deliver an electric current to the spinal cord, blocking pain signals.
Finally, there are herbal options, such as the Wellnee Herbal Knee Patch, which provides temporary relief for knee support and muscle pain.
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Drug-free treatments
Transdermal patches are used for various drug-free treatments. For example, a skin patch has been designed to use imperceptible electric currents to control microbes and combat bacterial infections. This opens up possibilities for drug-free treatments, especially for skin infections and wound healing. The patch, called Bioelectronic Localized Antimicrobial Stimulation Therapy (BLAST), contains electrodes and a hydrogel to provide an acidic environment. In a similar vein, electromagnetic cellularized patches have been used to promote neuronal differentiation and spinal cord injury repair.
Another example of a drug-free treatment using electrical patches is the Signal Relief Patch, which uses the natural electric field properties of the body to reduce pain. The patch is placed on or slightly above the most intense point of pain and uses neuro-capacitive technology to interact with the body's electromagnetic fields, recording and redirecting pain signals before they reach the brain. The Signal Relief Patch is drug-free, reusable, and does not require cables or batteries. It is made from medical-grade, latex-free materials, making it safe for all skin types.
Other drug-free treatments using electrical patches include EMS (Electrical Muscle Stimulation) patches, which are used for muscle pain relief and knee support. These patches are often made with natural herbs and can be used for temporary pain relief.
In addition to these applications, electrical patches have been used for transdermal drug delivery, particularly in the fields of diabetes, skin diseases, birth control, and wound healing. These patches can be passive or active, depending on the properties of the materials, design principles, and integrated devices.
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Frequently asked questions
Electrical patches are used for a variety of medical purposes, including treating bacterial infections, managing pain, and treating PTSD.
Electrical patches work by delivering a low electrical current to the skin, which can be used to deliver medication, control microbes, or send signals to the brain.
Electrical patches are generally safe for human use. The voltage used in electrical patches is significantly lower than the 15-volt limit deemed imperceptible and safe for humans.











































