
The heart is a pump made of muscle tissue, and its pumping action is controlled by electrical impulses. The cardiac conduction system is a network of nodes, cells, and signals that controls the heartbeat. The heart's electrical conduction system sends out thousands of signals per day to keep the heart beating. The heart nodes are specialized tissues that behave as both muscle and nervous tissue. The sinoatrial node (SA node) and the atrioventricular node (AV node) are the two main electrical nodes of the heart. The SA node is the heart's natural pacemaker, located in the upper wall of the right atrium, and it sends electrical impulses that start the heartbeat. The AV node, located near the central area of the heart, delays the SA node's electrical signal to ensure the atria are empty before the contraction stops.
| Characteristics | Values |
|---|---|
| Heart's natural pacemaker | Sinoatrial (SA) node |
| SA node location | Upper wall of the right atrium |
| SA node size | 15mm long, 4mm wide |
| SA node shape | Like a key |
| AV node location | Central area of the heart, near the bottom of the right atrium |
| AV node size | 5mm long, 5mm wide |
| AV node shape | Like a spindle |
| Function of AV node | Delays SA node's electrical signal by a fraction of a second to allow atria to contract before ventricles |
| Continuation of AV node | Bundle of His |
| Bundle of His | A branch of nerve cells that extends from the AV node to the Purkinje fibres |
| Bundle of His branches | Left bundle branch, Right bundle branch |
| Function of Purkinje fibres | Send electrical signals to the heart's right and left ventricles |
| Location of Purkinje fibres | Ventricle walls |
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What You'll Learn
- Sinoatrial (SA) node: The heart's natural pacemaker, it sends electrical impulses to start the heartbeat
- Atrioventricular (AV) node: Delays the SA node's electrical signal, allowing atria to contract before ventricles
- Bundle of His: A branch of nerve cells that carries electrical signals from the AV node to the Purkinje fibres
- Purkinje fibres: Rapidly transmit cardiac impulses to the myocardium of the ventricles, causing them to contract
- Autonomic nervous system: Controls the rate at which the SA node generates electrical impulses

Sinoatrial (SA) node: The heart's natural pacemaker, it sends electrical impulses to start the heartbeat
The Sinoatrial node, or SA node, is the heart's natural pacemaker. It is a cluster of cells that generate electrical impulses, which are sent through the heart's electrical conduction system, causing the heart to beat. The SA node is located in the upper part of the heart's right atrium, near the superior vena cava, a large vein that brings oxygen-poor blood from the body to the heart.
The SA node is responsible for initiating an action potential that results in an electrical impulse travelling through the heart. This impulse causes the heart's chambers to contract, pumping blood to the rest of the body. The rate at which the SA node sends electrical signals is controlled by the autonomic nervous system, which directs hormones that control heart rate based on physical activity and other factors. For example, during exercise or times of stress, the heart rate increases to meet the body's increased demand for oxygen.
When the SA node is functioning correctly, it ensures that the heart beats at a normal rate, typically between 60 and 100 beats per minute when a person is at rest. However, if the SA node malfunctions, it can cause the heart to delay or skip beats, beat too rapidly or slowly, or beat irregularly. In such cases, an artificial pacemaker may be required to regulate the heart's rhythm.
The SA node is an essential component of the heart's electrical conduction system, which includes other components such as the atrioventricular (AV) node, the bundle of His, and the Purkinje fibres. These structures work together to transmit and regulate electrical impulses, ensuring the heart contracts and relaxes in a coordinated manner.
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Atrioventricular (AV) node: Delays the SA node's electrical signal, allowing atria to contract before ventricles
The human heart is a pump made of muscle tissue. Its pumping action is controlled by electrical impulses that move through the heart, making it beat. This network of nodes, cells, and signals that controls the heartbeat is known as the cardiac conduction system.
The atrioventricular (AV) node is a small structure located near the central area of the heart. Its function is to connect the electrical systems of the atria and ventricles, providing electrical impedance from the atria and an intrinsic pacemaker in its absence. The intrinsic rate of the AV node is 40 to 60 beats per minute.
The AV node plays a crucial role in delaying the electrical signal generated by the sinoatrial (SA) node, which is the heart's natural pacemaker. When the impulses from the SA node reach the AV node, they are delayed by a consistent and very short amount of time, usually about a tenth of a second. This delay ensures that the atria, the upper chambers of the heart, have time to contract and empty the blood into the ventricles before ventricular contraction occurs.
After the delay, the AV node then sends the impulses down the atrioventricular bundle, also known as the bundle of His, to the ventricles. The bundle of His is a branch of nerve cells that extends from the AV node and carries the electrical signal to the Purkinje fibers. These Purkinje fibers are specialized branches that rapidly transmit the signal to the myocardium (middle heart layer) of both the left and right ventricles, causing them to contract and pump blood out to the body.
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Bundle of His: A branch of nerve cells that carries electrical signals from the AV node to the Purkinje fibres
The heart is a pump made of muscle tissue, and its pumping action is regulated by electrical impulses. The cardiac conduction system is a network of nodes, cells, and signals that controls the heartbeat. Electrical signals move through the heart, making it beat. The conduction system in the heart contains specialized cells and nodes that control the heartbeat.
The Bundle of His is a branch of nerve cells that extends from the atrioventricular (AV) node. The AV node is located near the central area of the heart and delays the sinoatrial (SA) node's electrical signal. The SA node is the heart's natural pacemaker and is located in the upper part of the heart's right atrium. It sends electrical impulses that start the heartbeat. The Bundle of His receives the electrical signal from the AV node and carries it to the Purkinje fibres.
The Bundle of His runs down the length of the septum (wall) that separates the right and left ventricles. The atrioventricular bundle has two branches: the left bundle branch and the right bundle branch. The left bundle branch sends electrical signals through the Purkinje fibres to the left ventricle, while the right bundle branch sends electrical signals to the right ventricle.
The Purkinje fibres are branches of specialized nerve cells that send electrical signals very quickly to the heart's right and left ventricles. They are located in the ventricle walls in the inner layer of tissue that lines the heart's chambers. When the Purkinje fibres deliver electrical signals to the ventricles, the ventricles contract, and blood flows from the right ventricle to the pulmonary arteries and from the left ventricle to the aorta.
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Purkinje fibres: Rapidly transmit cardiac impulses to the myocardium of the ventricles, causing them to contract
The heart is a pump made of muscle tissue, and its pumping action is regulated by electrical impulses. The cardiac conduction system is the network of nodes, cells and signals that controls the heartbeat.
The Purkinje fibres are a critical component of the heart's electrical conduction system. They are a network of specialised cells that are abundant with glycogen and have extensive gap junctions. These cells are located in the subendocardial surface of the ventricular walls, and they rapidly transmit cardiac action potentials from the atrioventricular bundle to the myocardium of the ventricles.
Purkinje fibres are larger than working cardiomyocytes and are more often larger and more rod-shaped than sinus and AV nodal cells. They are composed of electrically excitable cells and are essential for maintaining a healthy and consistent heart rhythm.
The Purkinje fibres receive the electrical signal from the atrioventricular (AV) node, which is located near the central area of the heart. The AV node delays the signal from the sinoatrial (SA) node by a fraction of a second, ensuring that the atria (upper heart chambers) are empty before the contraction stops. The Purkinje fibres then rapidly transmit the signal to the myocardium of the ventricles, causing them to contract. This rapid conduction allows for coordinated ventricular contraction and the efficient ejection of blood from the heart.
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Autonomic nervous system: Controls the rate at which the SA node generates electrical impulses
The human heart is a pump made of muscle tissue, and its pumping action is regulated by electrical impulses. The cardiac conduction system is a network of nodes, cells, and signals that controls the heartbeat. Electrical signals move through the heart, causing it to beat and regulating blood flow through the body.
The sinoatrial node (SA node) is the heart's natural pacemaker. It generates electrical impulses that set the rhythm and rate of the heart. The SA node is located in the upper part of the heart's right atrium, near the superior vena cava, a large vein that brings oxygen-poor blood from the body to the heart.
The autonomic nervous system plays a crucial role in controlling the rate at which the SA node generates electrical impulses. This system includes both the sympathetic and parasympathetic nervous systems. The sympathetic nervous system, often associated with the “fight or flight” response, increases the heart rate by making the SA node work faster. On the other hand, the parasympathetic nervous system, associated with the “rest and digest” response, slows down the heart rate by decreasing the SA node's activity.
The autonomic nervous system tightly regulates the input into the SA node. Autonomic fibers control the firing of the SA node, thereby influencing the heart rate. This regulation ensures that the heart rate corresponds to the body's needs, such as during physical activity or rest. Additionally, the autonomic nervous system works in conjunction with hormones and other factors to rapidly adjust the heart rate and cardiac output in response to the body's changing requirements.
In summary, the autonomic nervous system plays a vital role in controlling the rate of electrical impulse generation by the SA node, ultimately regulating the heart rate to meet the body's demands.
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Frequently asked questions
The heart's electrical nodes are known as the sinoatrial (SA) node and the atrioventricular (AV) node. These nodes work together to control the electrical impulses that regulate the heart's pumping action.
The SA node is the heart's natural pacemaker. It generates electrical impulses that initiate the heartbeat. Located in the upper wall of the right atrium, it sends impulses across both atria, resulting in atrial contraction.
The AV node is responsible for delaying the electrical signal from the SA node by a fraction of a second. This delay ensures that the atria empty blood into the ventricles before the ventricles contract.
After the AV node, the electrical impulse travels through the bundle of His, a branch of nerve cells. This bundle carries the signal down the septum that separates the right and left ventricles.
Purkinje fibres are specialised branches of nerve cells found just beneath the inner layer of the ventricle walls. They rapidly transmit the electrical impulses from the bundle of His to the myocardium (middle heart layer) of the ventricles, causing them to contract and pump blood out of the heart.































